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Some budding yeast species have the ability to silence genes using RNA interference (RNAi). Until now, most researchers thought that no budding yeasts possess the RNAi pathway because Saccharomyces cerevisiae, the protoypical model budding yeast does not.

Whitehead Institute scientists have developed a rapid, inexpensive drug-screening method that could be used to target diseases that until now have stymied drug developers, such as Parkinson’s disease.  This technique uses baker’s yeast to synthesize and screen the molecules, cutting target discovery and preliminary testing time to a matter of weeks.